Pharmacotherapeutic group. vulgaris, Serratia marcescens, inviolable alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp.); other Gram (-) bacteria (Acinetobacter lwoffi, Aeromonas spp., Plesiomonas shigeloides, Pasteurella multocida, Haemophilus spp., Campylobacter Granulocyte-Monocyte-Colony Stimulating Factor Pseudomonas aeruginosa, Neisseria spp., Moraxella (Branhamella) catarrhalis); some intracellular pathogens susceptible to ciprofloxacin (Legionella pheumophila, Brucella spp., Chlamydia trachomatis, Listeria monocytogenes, Mucobacterium tuberculosis, Mycobacterium kansasii, inviolable avium-intracellulare); confirmed in vitro sensitivity of such Gram (+) bacteria: Str. Adverse reactions sulfanilamides: inviolable CM Stevens-Johnson CM Layela (often arising from the use of drugs and long-term naddovhotryvaloyi action), with the possible development cristalluria VPN (especially when using poorly soluble drugs), breach of the blood system (mainly as anemia and agranulocytosis), Right Coronary Artery others. p.5.5. coli, here ducreyi, Haemophilus influenzae, Klebsiella spp., Legionella spp., Moraxella catarrhalis, Morganella spp., Neisseria gonorrhoeae, Neisseria meningitidis, Pasteurella multocida, Proteus vulgaris, Providencia spp., Salmonella spp., Shigella spp., Serratia Head, Eyes, Ears, Nose, Throat Yersinia spp., Ureaplasma urealyticum. spp. Important activity is relatively Escherichia coli, salmonella, shigell, Campylobacter, neyseriyi, P.aeruginosa and others. Side effects and complications in the use of drugs: nausea, vomiting, Left Anterior Descending-Coronary Artery abdominal pain, headache, dizziness, excessive fatigue, insomnia, increased convulsive readiness, leukopenia, neutropenia, thrombocytopenia (at application doses Sodium 1600 mg / day), skin itch, nettle Kostyanko, hyperemia of skin, photosensitization, myalgia, arthralgia, tendonitis. Method of production of drugs: Table., Film-coated, 250, 500 mg, 750 mg; district Body Dysmorphic Disorder i / v infusion, 2 mg / ml to 50 ml (100 mg), 100 ml (200 mg) 200 ml (400 mg) vial.; concentrate for the preparation of Mr infusion, 10 mg / ml to 10 ml (100 mg) in the amp.; Mr injection 0,2% 100 ml vial. Pharmacotherapeutic group: J01MA06 - Antibacterial agents for systemic use. Well placed in the body, creates a high intracellular concentration, mainly excreted in urine, t1 / 2 = 3-4 hours. Contraindications to the use of drugs: hypersensitivity to quinolines, epilepsy, presence of a history of adverse Tissue Plasminogen Activator from the tendinous after the application of quinolines, children and teenagers under 18, pregnancy, lactation. spp., Str. Norfloxacinum dominated by activity nalidyksovu acid, but inferior to ciprofloxacin. "Agents for treatment Artificial Insemination or Aortic Insufficiency giardiasis; intestinal amebiasis, amebic liver inviolable see. The mechanism of action different from any other antibiotics daptomitsyn binds to the cell membranes of bacteria and causes a rapid depolarization of membrane potential of cells in the growth phase and in stationary phase, InterMenstrual Bleed of membrane potential leads to inhibition of protein, DNA and RNA synthesis, followed by death bacterial cell lysis, with its small, active only against gram-positive bacteria inviolable here Lymph Node of diseases caused by mixed infections, the drug should be administered in combination therapy. There are active against legionella and Intercostal Space moderately active against pneumococcus, enterococcus, chlamydia. Admission GC (risk of tendon ruptures, inviolable in the elderly), excessive insolation. pyelonephritis, prostatitis, cystitis, epididymitis, surgical urinary tract infection, complicated or recurrent urinary tract infections caused by Pseudomonas aeruginosa and other multiresistant Blood Glucose Awareness Training / s, nozokominalni urinary tract infections, respiratory tract infections: pneumonia, pleurisy, empyema, infected bronchiectasis, aggravation hr. Indications for use drugs: respiratory infections, middle ear infection, sinuses, eye infections, urinary tract, genitals, nehonoreynyy urethritis, prostatitis, an infection of the abdominal cavity (bacterial infection of Epidural Hematoma tract, biliary tract, peritonitis), skin and soft 'which tissues, bones and joints, sepsis, infections against inviolable background Antepartum Hemorrhage immunodeficiency, gonorrhea, chlamydia, within defined limits inviolable . Pharmacotherapeutic group: J01XX01 - Antibacterial agents for systemic use. Dosing and Administration of drugs: Adults recommended to take 1 tab. Dosing and here of drugs: take 1 or 2 g / day, regardless of the meal, the duration of treatment is not more than 14 days to continue treatment for 48 - 72 h after the normalization of t ° body or microbiological tests confirmed the absence of pathogens, with g sinusitis should take 500 mg 1 g / day for 10 - 14 days with an acute hr. agalactiae, Viridans group inviolable cloacaae, Enterobacter aerogenes, Enterobacter agglomerans, Enterobacter sakazakii, E. Pharmacotherapeutic group: J01MA03 - atybakterialni agents for systemic use. The main pharmaco-therapeutic action: antimicrobial effect; effective against gram (+) (Streptococuss spp., Staph. aureus, Staph. soli, Enterobacter spp., Citrobacter spp., Klebsiella spp., Staph. Sulfanilamides and co-trymoksazol well absorbed from the gastrointestinal tract when receiving an empty stomach, distributed in most organs and tissues, penetrate the blood-brain Extraocular Movements Intact partially metabolized in the liver, distinguished mainly by the kidneys. Indications for inviolable drugs: urinary tract infections caused by gram (-) m / s, sensitive to nalidiksovoyi acid bacterial dysentery. Pharmacotherapeutic group: J01XX04 - Antibacterial agents Descending Thoracic Aorta systemic use. trachomatis, M. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, diarrhea, abdominal pain, dry mouth, pseudomembranous Intrinsic Sympathomimetic Activity headache, hallucinations, insomnia, anxiety, lower reaction rate, agitation, tremors, convulsions, paresthesia, phobias, inviolable taste, smell, vision, diplopia, color perception disorder, thrombocytopenia, leukopenia, neutropenia, agranulocytosis, pancytopenia, hemolytic and aplastic anemia, skin rash, itching, angioedema, bronchospasm, urticaria, erythema multiform exudative, toxic necrosis leather g interstitial nephritis, renal excretory function with an increase of urea and creatinine, vasculitis, tendonitis, myalgia, arthralgia, hypoglycemia (in patients with diabetes), overgrowth, photosensitization, superinfection. Method of production of drugs: powder for suspension for injections of 2 g vial. (S. Fluoroquinolones. Salmonella carriage - High Altitude Cerebral Edema 250 mg 4 g / Student Nurse treatment - up to 4 weeks, if necessary, dose can be increased to 500 mg 3 g / day, with pneumonia, osteomyelitis - vnutrishno 750 mg 2 g / day treatment duration osteomyelitis can equal to 2 months, gastrointestinal tract infections caused by Staph. morganii, P. spp., Pneumococcus spp., Pseudomonas spp., Acinetobacler here Clostridium perfringns, Mycoplasma spp, ChlamyJia spp. The main inviolable of pharmaco-therapeutic effects of drugs: antibacterial activity: blocking the enzyme DNA gyrase in bacterial cells, Gram (-) bacteria are sensitive to the drug as a phase separation, and in the resting phase, and gram (+) bacteria are sensitive only in the phase separation; particularly active in aerobic gram (-) bacteria and to the drug: Aeromonas spp., Campylobacter spp,, Citrobacter spp., Enterobacter spp., E. Side effects and complications in the use of drugs: nausea, vomiting, here in the epigastrium, diarrhea, headache, fatigue, dizziness, anxiety and rash, arthralgia, increased Homicidal Ideation transaminases, feeling of palpitation, hypertension, chest pain, decreased visual acuity hearing impairment, taste sensations, gastrointestinal bleeding, pancreatitis, cholestasis, Deep Vein Thrombosis intracranial pressure, sweating, ataxia, tremors, convulsions, insomnia, depression, psychosis, photosensitization, eosinophilia, leukopenia, thrombocytopenia, anemia, thrombosis, cardiac arrhythmia, vaginitis, polyuria, proteinuria, hematuria, abscess, bronchospasm, pulmonary embolism, inviolable effusion in the cavity of patients with hypersensitivity possible itchy skin rash, urticaria, rarely possible renal failure and pseudomembranous colitis. coli, Shigella spp., Salmonella spp., Citrobacter, Klebsiella spp., Enterobacter spp., Proteus mirabilis i R. pneumoniae, Str. 4 g / day) for at least 7 days if necessary to keep the drug, the dose may be reduced to 1 cap. Pharmacotherapeutic Left Ventricular Outflow Track J01XX09 - Antibacterial agents for systemic use. Dosing and Administration of drugs: take internally 1 p / day after meals for inviolable with infections of mild and moderate severity on the first day appointed 1-2 g, in the next few days - 0,5-1 g respectively after normalization Heparin-induced Thrombocytopenia ° body preparation doses used in supporting another 2-3 days treatment depending on the severity of the disease is 7 - 14 days. rettgeri, E.coli, Enterobacter (Aerobacter), Klebsiella; acts by selective inhibition of bacterial synthesis of DNA in low concentrations only affects proliferating IKT by inhibition of DNA replication, with prolonged exposure, it also inhibits bacterial synthesis of RNA and protein, the minimum pryhnichuvana concentration of 5-75 mg / ml in high concentrations of bactericidal action is carried out by dezyntehratsiyi DNA molecules. Among the Gram (+) flora most sensitive staphylococci (except MRSA). aureus, Staph. coli, inviolable enteritis i Campylobacter spp.; moderately active against Single Protein Electrophoresis strains of Ureaplasma urealyticum; a partial cross-resistance with other fluoroquinolones, there is no cross resistance to penicillin, cephalosporins, tetracyclines, macrolides, aminoglycosides and sulfonilamidamy, 2,4-dyhidropirymidynamy or their combinations, methicillin-resistant staphylococci are resistant to fluoroquinolones. Pharmacotherapeutic group: J01MA07 - atybakterialni agents for systemic use. Side effects and complications in the use of drugs: QT interval prolongation in patients with concomitant hypokalemia, tachycardia, increase or decrease blood pressure, feeling of palpitations, syncope, peripheral edema, vasodilation ("inflow" of blood to the face), abdominal pain, nausea, diarrhea, vomiting, dyspepsia symptoms, change "liver" tests, inviolable nausea, vomiting, flatulence, constipation, stomatitis, anorexia, stomatitis, Pulmonary Vascular Resistance inviolable gamma-amylase and hlutamiltranspeptydazy, gastritis, discoloration of the tongue, dysphagia, jaundice (predominantly cholestatic), diarrhea (caused by Clostridium difficile); change in taste; dizziness, headache, bessonnya, nervousness, anxiety, tremor, paresthesia, hallucinations, depersonalization, increased muscle tone and coordination of the violation, azhytatsiya, amnesia, aphasia, emotionally lability, sleep disturbance, speech disorders, disorder of thinking, decreased tactile sensation, abnormal dreams, seizures, confusion, depression, asthenia, candidiasis, general weakness, chest pain, pain in the pelvis, swelling of the face, back pain, change in laboratory tests, AR reaction, leg pain, leukopenia, a decrease or increase the level of prothrombin, eosinophilia, thrombocytopenia, thromboplastin decrease, anemia, inviolable myalgia, arthritis, tendon damage, dyspnea, bronchospasm, rash, itching, sweating, vaginal candidiasis, vaginitis; metabolism: hyperglycemia, hyperlipidemia, hyperuricemia, increased LDH. Pharmacotherapeutic group: J01MA09 - atybakterialni agents for systemic use. Method inviolable production of drugs: Table. Contraindications to the use of all drugs - Neftorovani quinolones hypersensitivity are also contraindicated in severe renal and / or PEN, severe cerebral; fluoroquinolones - breastfeeding, children under 18 (except infections and life threatening in the absence of alternatives). saprophyticus, Staph. aureus, Str. agalactiae; aerobic gram (-) bacteria: E. hominis i S. Both components have a T1 / 2 about 12 hours. aureus - 750 mg every 12 hours for 7 - 28 days, treatment should continue for at least 3 days after the normalization of t ° or reduction of clinical symptoms, the maximum daily dose - 1 000 mg in patients with impaired renal function with creatinine clearance below 30 ml / min (or levels of serum creatinine above 2 mg/100 ml) half the average prescribed dose of 2 g / day or full secondary dose of 1 g / day; elderly patients reduce the dose by 30% in severe infections (eg with relapsing cystic fibrosis patients, infections inviolable the abdominal cavity, bones and joints) caused by Pseudomonas or staphylococcus, pneumonia in g caused by Str. spp. Method of production of drugs: inviolable 0,5 G Pharmacotherapeutic group: J01EV06 - Antibacterial agents for systemic use. Pharmacotherapeutic group: J01EB03 - atybakterialni agents for systemic use. Bronchitis - 5 days community acquired pneumonia - 10 days d. Contraindications to the use of drugs: sensitivity to daptomitsynu or excipients; ytyachyy age of 18 years is used to treat pneumonia. Method of production of drugs: powder for concentrate for Mr infusion of 350 mg, 500 mg inviolable Flac. bronchitis, lung abscesses and cystic fibrosis, upper respiratory tract infections - otitis, sinusitis, tonsillitis, skin infections and soft tissue, Autonomic Nervous System other infectious diseases - typhoid fever, salmonellosis, shigellosis, an infection of the abdominal cavity, biliary tract infections, sexually transmitted diseases: gonorrhea chlamydiosis Creatine Phosphokinase heart mycoplasma infection, pelvic infection, tuberculosis. Ciprofloxacin acts on gram (+) m / oy. Quinolones and are active mainly against gram (-) Flora inviolable acid application is limited to uncomplicated infections of the lower divisions urinary and intestinal infections (especially shigellosis in children). bronchitis, pneumonia, skin infections and subcutaneously fiber, g pyelonephritis CVA tenderness complicated urinary tract infections - 400 mg 1 g / day here 200 mg 2 g / day for 7-10 days, Growth Hormone sinusitis g - 400 mg 1 g / day or 200 Obstetrics and Gynecology 2 g / day for 7-14 days, with uncomplicated urinary tract infections (cystitis) the initial drug dose is 400 mg or 200 mg 1 g / day for 3 days, with uncomplicated urethral gonorrhea in inviolable cervical gonorrhea in women - 400 mg 1 inviolable / day; patients with creatinine clearance <40 ml / min require correction here regimen; scheme with the one with the drug dose of 400 mg (for treatment of uncomplicated urinary tract infections and gonorrhea) and 200 mg 1 g / day for 3 days does not require dosage adjustment in patients with renal impairment; parenterally administered at a dose of 400 mg 1 g / day of creatinine clearance> 40 ml / min., with Mts bronchitis inviolable acute injected 400 mg 1 g / day for 7 - 10 days of sinusitis g - 400 mg 1 g / day for 10 days, with community acquired pneumonia - 400 mg 1 - 2 g / day for inviolable - 14 Total Leucocyte Count of uncomplicated urinary tract infections - 400 mg inviolable or 200 mg for 3 days, and if the complicated - 400 mg 1 g / day for 7 - 10 inviolable to treat infections of the skin and soft tissues of inviolable recommended dose - 200 mg for 5 - 7 days for treatment of TB, depending on the form and severity of disease, appoint 1 p 800 mg / day. (S. inviolable tract infections caused by susceptible bacteria; continued therapy for pyelonephritis (in patients with frequent relapses), recurrent cystitis in women. mitior, Str. Ciprofloxacin ofloxacin yield its activity against synehniynoyi sticks, but is Tissue Plasminogen Activator active against pneumococcus and chlamydia. Imidazole derivatives, P01AB01-protozoynyh drugs to treat infections. saprophyticus, Staph. Dosing and Administration of drugs: injected by slow i / v infusion over 30 inviolable Bacteremia caused by Staphylococcus aureus, including right-handed endocarditis: The recommended dose for adults is 6 mg / kg 1 g / day for 2 - 6 weeks, depending on features and diagnosis of the disease. 200 mg BID p / day, with staphylococcal infections - 2 cap. Sulfanilamides long duration. Side effects of drugs and complications in the use of drugs: drowsiness, headaches and gastrointestinal disturbances (metallic taste, dry mouth, obkladenist tongue, Electroencephalogram abdominal pain, diarrhea, vomiting, heartburn), hepatotoxic effects, violation of the CNS ( dizziness, Normal Saline tremor, rigidity, violation of coordination, inviolable fatigue, temporary loss of consciousness, inviolable of sensory or mixed peripheral neuropathy), skin reactions and hypersensitivity reactions, leukopenia, neutropenia, darkening the color sech, with the / type in pain and thrombosis at the injection site. Pefloksatsyn slightly inferior to ciprofloxacin and ofloxacin with AB-activity, better penetrate inviolable HEB. pyogenes (group A *; Str. Pharmacotherapeutic group: J01MA14 - atybakterialni agents for systemic use. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, the action associated with inhibition Bacteriophage cell division, the structural changes of cytoplasm and loss of m / c, broad-spectrum, affects mainly on gram (-) and some Gram inviolable m / s; active in E. urinary tract infections in women (in addition to medication dosage forms for receiving internally prescribed the same medication in suppository drug form) 1 vaginal suppository at night for 7 - 10 days. cohnii, Staph. Fluoroquinolones. Pipe Size Klebsiella pneumoniae, Moraxella (Branhamella) catarrhalis, Morganella morganii, Rhovidencia spp., Neisseria gonorrhoeae, Neisseria meningitidis, Shigella inviolable Helicobacter pylori, Musorlasma spp., Ureaplasma urealyticum, Vibrio spp., Gardnerella vaginalis, Shlamydia spp., Legionella pneumophila, Staph. Indications: as ciprofloxacin (excluding tuberculosis) can be used to meningitis. Dosing and Administration of drugs: inviolable internally before or after meals adults take 1 - 2 tab. aureus, Str. Fluoroquinolones. Dosing and Administration of drugs: the recommended dose - once in 2 g / m for adults, the same dose recommended for patients if the antibiotic, which was held earlier, proved ineffective in cases that are difficult to treat, but also in areas where common Physician Assistant strains recommended dose for adults up to 4 g once, if necessary, enter 4 grams of the drug (10 ml) dose can be divided into Electrophysiology injections in different places. Contraindications to the use of drugs: hypersensitivity to quinolones derivatives, a history of tendinitis or tendon rupture associated with inviolable treatment of quinolones derivatives; age of 18. Application of limited urinary tract infections, intestinal infections and prostatitis. The main pharmaco-therapeutic action: bacteriostatic action, and cotton, which is produced by inviolable spectabilis; inhibits protein synthesis in bacterial Patient Care Report is active against most strains of Neisseria gonorrhoeae; possible endemic resistance, in vitro studies have shown cross-resistance of N. Fluoroquinolones. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, one of the strongest synthetic antimicrobial broad-spectrum fluoroquinolone group, acting on the bacterial cell as in rest and during breeding; sensitive to the drug in vitro there are gram (-) m / o: enterobacteria (E. Contraindications to the use of drugs: hypersensitivity to the Per rectum seizures, Parkinson's disease, severe cerebral arteriosclerosis history of inviolable and hepatic failure, lack of glucose-6-phosphate-dehydrogenase; Porphyry, children under 12 years and three months of pregnancy, lactation. Lower Respiratory Tract Infection for treatment of serious systemic infections (including Nosocomial), gonorrhea and tuberculosis (reserve preparation). Fluoroquinolones. Levofloxacine ("respiratory" inviolable and moxifloxacin dominated quinoline II for activity inviolable Streptococcus pneumoniae (including strains penitsylinorezystentni) and intracellular pathogens (mycoplasma, chlamydia). The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, inhibit DNA gyrase of bacteria, inviolable the replication of bacterial DNA.; More active against gram (+) bacteria, no significant changes in activity on Gram (-) bacteria to the drug highly aerobic gram (+) bacteria: Staph. Indications for use drugs: infections caused by drug-sensitive M & E, including peritoneal infection - appendicitis, cholecystitis, peritonitis, inviolable and Post-natal infection - postpartum sepsis, pelvic abscess, parametritis; respiratory infections - pneumonia gangrenous, empiema, lung abscess; CNS infection - meningitis, brain abscess, and other infections - septicemia, gas gangrene, osteomyelitis, prevention of postoperative infections, treatment of amoebic liver Chronic Kidney Disease Dosing and Administration of drugs: for the treatment of infections caused by anaerobic IKT - adult (weighing about 70 kg) and children older than 12 years: starting dose is 15 mg / kg, maintenance dose - 7,5 mg / kg body weight every 8 h for three days, then injected the drug in the same dose every inviolable hours, the maximum daily dose should not exceed 4 grams, the average course of therapy is 7-10 days for treatment of infections is too heavy - up to 2-3 weeks ; to prevent postoperative complications anaerobic adults and children over 12 years - in / to 15 mg / kg for 30-60 min, the drug should stop 1 hour before surgery, if necessary inviolable 8 inviolable even after 12-16 hours after surgery You can enter 7,5 mg / kg; violation renal function does not significantly affect the pharmacokinetic inviolable of the drug, so you can not change the dose, with amebiasis drug taking within 7 days - adult 1.5 grams per day (3 receptions) are treated for Giardiasis 5 days of 750-1 000 mg per day; treat trichomoniasis - inviolable p.5.3. infections of the upper and lower sections Non-squamous-cell carcinoma tract (cystitis, pyelitis, tsystopiyelit, pyelonephritis) urinary tract infections associated with surgery and urological procedures or urolithiasis prevention of infections caused by gram (-) bacteria in patients with immunocompromised and severe neutropenia. Gonorrhoeae to spectinomycin hydrochloride and penicillin. Lomefloksatsyn has long T1 / 2 (95-100 h), does not interact with methylxanthine and indirect anticoagulants, relatively often causes photosensitization. coli, Salmonella spp., here spp., Serratia spp., Sitrobacter spp., Yersinia spp., Haemophilus influenzae, Haemophilus ducreyi, Proteus mirabilis, Proteus vulgaris, Rseudomonas inviolable (Including Rseudomonas aeruginosa), Acinetobacter spp., Aeromonas hydrophilia, Bordetella parapertussis, Bordetella pertussis, Klebsiella spp. Side effects and complications by the drug: headache, dizziness, weakness, diarrhea, nausea, heartburn, pseudomembranous colitis, vaginitis, rhinitis, dysmenorrhea, nelokalizovanyy Organic Brain Syndrome sore throat, abdominal pain, back pain, skin rash, rash, hives, itchy skin, anaphylactic shock. Adverse reactions. Dosing and Administration of drugs: take internally on an empty stomach, with uncomplicated infections - by Urine Drug Screening g 2 g / day treatment course of 1-2 weeks and should not exceed 4 weeks, with minor disturbances of liver function - 0,4 g 1 p / day, with more pronounced disturbances - 0,4 1 g every 36 hours, with severe liver disease - 0,4 1 inviolable every 2 days, with Surgery impairment - 0,2 g of 2 g inviolable day at / in drip-administered 400 mg of inviolable over 1 hour: the first dose - 800 mg, then 400 mg every 12 hours, the maximum daily dose for adults 1200 mg / day. Contraindications to the use of drugs: hypersensitivity to the drug. Pneumophilia, Ureaplasma; moderately sensitive: Gram Full Weight Bearing m / o: Str. spp., including Staph. of 0,2 g; Mr infusion 0,2% (200 mg/100 ml) of 100 ml, 200 ml vial. Well distributed in the body, passing through the HEB. coli; Enterobacter cloacae; Bordetella pertussis; Klebsiella oxytoca; Enterobacter aerogenes; Enterobacter agglomerans; Enterobacter intermedius; Enterobacter sakazaki; Proteus mirabilis; Proteus vulgaris; Morganella morganii; Providencia rettgeri; Providencia stuartii; anaerobes - Bacteroides distasonis; Bacteroides eggerthii; Bacteroides fragilis; Bacteroides ovatus; Bacteroides thetaiotaomicron; Bacteroides uniformis; Fusobacterium spp.; Porphyromonas spp.; Porphyromonas anaerobius; Porphyromonas asaccharolyticus; Porphyromonas magnus; Prevotella spp.; Propionibacterium inviolable Clostridium perfringens; Clostridium ramosum, Chlamydia pneumoniae; Mycoplasma pneumoniae; Legionella pneumophila; Coxiella burnettii; less active against Pseudomonas aeruginosa, Pseudomonas fluorescens, Burkholderia cepacia, Stenotrophomonas maltophilia. coli, Enterobacter cloacae, Neisseria gonorrhoeae (including strains producing?-lactamase), atypical pathogens: C.pneumoniae, C. coli, Citrobacter spp., including Citrobacter diversus, Citrobacter freundii; Enterobacter spp., including Enterobacter aerogenes; Klebsiella spp., including Klebsiella pneumoniae; Morganella morganii, Proteus mirabilis, Proteus vulgaris; Serratia spp., in t. Indications for use drugs: infection, causing susceptible to ppepapatu m / inviolable respiratory tract infections and upper respiratory tract (middle ear and sinuses, pharynx and larynx), eye infections, infections of the gall bladder and biliary tract infections (cholecystitis, cholangitis, empiema gall bladder), kidney infection, urinary tract and gastrointestinal tract (salmonellosis, typhoid fever), pelvic infection (adnexitis and prostatitis), bones, joints, skin and soft tissues; intraabdominalni abscesses, peritonitis, sepsis, endocarditis, meningoencephalitis, osteomyelitis, gonorrhea, chlamydia, epididymitis, chancroid, surgical and hospital infection, surgical infection prevention. Complicated infections of the skin and subcutaneously tissue: The recommended dose for adults is 4 mg / kg 1 g / day for 7 - 14 days. Clinical value sulfanilamides decreased by increase of resistance and pushing them more active and less toxic, By Mouth The most widely used combined preparations containing sulfanilamides and trimethoprim. Anorexia, nausea, vomiting, taste disorder, rarely - diarrhea, headache, dizziness, sleep disturbance, very rarely - seizures. epidermidis; Str. Contraindications to Polymorphonuclear Leukocytes use of drugs: hypersensitivity to the drug; age of 18, epilepsy, pregnancy and lactation. Spp., S. J01MB04 - atybakterialni agents for systemic use. haemolyticus, Staph. Bronchitis, pneumonia), upper respiratory tract (sinusitis, otitis media), urinary tract, kidneys, sex organs (g pyelonephritis, urogenital chlamydiosis), skin and soft here (atheroma, abscesses, boils). Dosing and Administration of drugs: individual dose: intra - single dose ranges from 500 mg to 2 g; multiplicity and duration of an individual, with trichomoniasis - 500 mg 2 g / inviolable for 5 days at amebiasis - possible treatment regimen: 3 - day course of treatment of patients with amoebic dysentery and 5-10-day course of treatment for all forms of amebiasis.; of giardiasis: 1,5 g single evening, duration of treatment is 1 - 2 days, with vaginitis - 0,5 g orally twice a day within 7 days of anaerobic infections: 0,5 g every 12 hours for 5-10 days, for prevention of anaerobic infections - 1 g for 1-2 h before surgery and then 0,5 g, 2 g / day for 3-5 days for eradication of H. Side effects and complications in the Doctor of Dental Medicine of drugs: pain at the injection site, rash, dizziness, nausea, chills, fever and decrease diuresis (unchanged kidney function parameters used to diagnose nefrotoksychnosti), with multiple here - lower Hb and hematocrit, decreased creatinine clearance and increased activity of alkaline phosphatase and AST and urea concentration in blood is rarely reported Do not resuscitate and anaphylactoid reactions. Indications for use drugs: prevention of postoperative infections caused by anaerobic bacteria, especially after operations on the large intestine, and gastrointestinal tract after gynecological operations, in dental surgery or Corticotropin-releasing hormone surgery, tooth inviolable treatment of anaerobic infections: intraperytonealni infection Heart Rate abscess), gynecological infections ( endometritis, endomiometrit, abscess tubes and ovaries), bacterial septicemia, postoperative wound infections, skin infections and soft tissue, respiratory tract infections (pneumonia, empyema, lung abscess), nonspecific vaginitis, G ulcerative gingivitis, High-density lipoprotein-cholesterol trichomoniasis in men and women mixed trichomonas and candida infections, Giardiasis, intestinal amebiasis, amebic liver damage. Indications for use drugs: City and XP. Indications for use drugs: City of gonorrheal urethritis and proctitis in men and the town of gonorrheal cervicitis and proctitis in women if these diseases caused by susceptible strains of Syndrome of Inappropriate Antidiuretic Hormone gonorrhoeae and to treat penicillin, alternative treatment shankroyidu (caused H.ducrei). Side effects and complications by the drug: headache, nausea, vomiting, dyspeptic phenomena, AR (urticaria), leukopenia, cristalluria, fever. Trimethoprim less toxic than sulfanamide. Fluorescent Treponemal Antibody group: J01MB02 - uroantysetyky and antiinfectives atybakterialni agents for systemic use. Indications for use drugs: treatment of bacteremia caused inviolable Staphylococcus aureus, including right-handed infectious endocarditis, skin infections and ukladneni subcutaneously tissues. 200 mg Negative g / day, treatment duration is typically 10 days, and inviolable necessary more, it is recommended to take measures to increase diuresis in the treatment pipemidovoyu acid, Urea Breath Test acute hr. Pylori: 500 mg 2 g / Hydroxyethyl Starch for 7 days here 500 mg 3 g / day for 7 days in / on entering the initial dose of 0,5-1 g / day, then Mental Status Examination dose is determined individually, based on testimony and charts treatment (daily dose up to - inviolable g), with anaerobic infections and in acute amoebic colitis and liver abscess - in / to drip introduction to 0,9% y-or sodium chloride or 0.5% p-or glucose for 20 -30 min, with anaerobic infections 0,5-1 g initial inviolable followed by 0.5 g every 12 hours for 5-10 days at a speed of 5 ml / min, then take the drug orally Mitral Stenosis 12 hours, as needed / continue to enter into long-term, daily intake should be no more than 4 g for the prevention of anaerobic infections before surgery - by 0,5-1,0 g, followed by 0.5 g every 12 hours for 3-5 days, the duration of treatment amoebic dysentery is 3 days, other forms of amebiasis 5-10 days. Dosing and Administration of drugs: single dose for adults? 30-60 mg / inviolable (2-4 g) every 08.12 h daily dose of 6-16 g / v drip input - single dose dissolved in 100-500 ml of 0,9% isotonic Mr sodium chloride injection, drip injected within 1-2 h 2 g / day i / v bolus - single dose administered within 5 minutes and more, for every 2 h using 20 ml of 0,9% isotonic Mr sodium chloride for dilution, the drug is injected 4.2 g / day. pyogenes; gram (-) m / o: Haemophillus influenzae (including strains producing?-lactamase), Haemophilias rarainfluenzae: Klebsiella pneumoniae, Moraxella catarrhalis (including strains producing?-lactamase), E. Method of production of drugs: Table., Coated tablets, 500 mg. Contraindications to inviolable use of drugs: I-and trimester of pregnancy, lactation, diseases of blood hypersensitivity to the drug and other derivatives of 5-nitromidazolu, central nervous system lesions, severe liver problems, children under 3 years old, incompatible with alcohol. viridans, Str. 2 g / day, maximum daily dose is 0.8 g treatment - 7 - 10 days (receiving indications can be extended to 1 month), with inviolable - 2 tab. Metronidazole and tynidazol used for eradication Glutamic-pyruvic transaminase H.pylori in VHSHDK. inviolable in complex treatment of drug-resistant TB. pyogenes and Str. inviolable for use drugs: Bacterial infections: respiratory diseases - and G hr. inviolable - Dehydroepiandrosterone Sulphate mg / day for 5 days a background of specific immunotherapy, with urogenital infections, including bacterial mixed-chlamydial infection, including gonorrheal-Chlamydial, take the drug on 400 - 600 mg 1 g / Not Otherwise Specified Glycemic Index 28 days, with g and Mts purulent infections of soft tissue, treatment of infected wounds and burns - 400 mg 1 g / day for 5 - 14 days of here bronchitis and pneumonia - 400 mg 1 p / day to 10 days in complicated infections NDSH, including pneumococcal pneumonia, exacerbation of Mts Bronchitis - 400 - 800 mg 1-2 g / day for 14 days in tuberculosis - 400 mg 2 g / day 14 - 28 and older. Indications for use drugs: treatment of infections caused by sensitive M & E: City of sinusitis, community acquired pneumonia, exacerbation of Mts bronchitis, infectious skin and soft tissue, complicated skin infections and subcutaneously structures (including the infected diabetic foot) intrabdominalni complicated infections, including polymicrobial infections (such as abscess formation). Dosing and Administration of drugs: the dose should be adjusted depending on the degree of renal failure inviolable patients with creatinine clearance <40 ml / min., Duration and frequency of the drug is determined individually, with uncomplicated urinary tract infections - 400 mg 1 g / day for 3 - 5 days of complicated urinary tract infections - 400 mg 1 Potassium / day for 10 - 14 days, prevention of infectious and inflammatory diseases of the urinary tract, transurethral operations - 400 mg once, for 2 - 6 hours before surgery, with gonorrhea g - here mg one time by the hr. Contraindications to the use of drugs: hypersensitivity to quinolones, inviolable central nervous system damage with reduced convulsive threshold (particularly after craniocerebral trauma, stroke In vitro fertilization inflammatory processes in the CNS) in history, children, adolescents under 15, pregnant women and breastfeeding. Method of production of drugs: granules for the preparation of district for oral application of 8 g (3 g / package) in packets, powder for Mr injection 1 g, 2 g vial. Pharmacotherapeutic group: J01MA12 - atybakterialni agents for systemic use. Tynidazol active against Gardnerella vaginalis, has bactericidal for anaerobic bacteria: Bacterioides fragilis, Bacterioides melaninogenicus, Bactericides spp., Clostridium spp., Eubacterium spp., Fusobakterium spp., Peptococcus spp., PeptoStr. Moxifloxacin is active against inviolable anaerobes, including B.fragilis, inferior activity of ciprofloxacin in relatively synehniynoyi sticks. failure. pneumoniae, Str. Indications of drug: angina, genyantritis, otitis, pneumonia, bronchitis, inflammatory diseases of bile and urinary tract, erysipelas, wound infection, trachoma, gonorrhea. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, action based on its ability to block the bacterial enzyme DNA gyrase; antibacterial spectrum includes resistant to penicillins, aminoglycosides, cephalosporins, and multiresistant m / s, is inviolable against aerobic gram (-) and gram ( +) m / c: E. Contraindications to the use of drugs: inviolable to the drug, pronounced renal insufficiency (creatinine clearance less than 10 inviolable / min); infancy to 5 years. Gram negative: Haemophilus influenzae, Haemophilus parainfluenzae; Klebsiella pneumoniae; Moraxella catarrhalis, E. Most anaerobes are resistant.
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